Inhibitory test of soursop fruit extract (Annona muricata L) against clinical isolates of Candida albicans from the users of heat polymerized acrylic resin denture

Uji daya hambat ekstrak buah sirsak (Annona muricata l) terhadap isolat klinik Candida albicans dari pengguna gigi tiruan resin akrilik polimerisasi panas

Abstract

Health problems that often occur due to the use of dentures are denture stomatitis. Candida albicans is a microorganism in the oral cavity with the highest
prevalence in denture stomatitis. One herbal ingredient that can be used as an alternative denture cleaner is soursop fruit (Annona muricata L). This labo
ratory experimental study used a post-test control group design to provide data on the inhibitory effect of soursop fruit extract on the growth of C.albicans.
The samples were C.albicans suspensions obtained from clinical isolates of heat-polymerised acrylic resin (HPAR) denture users, which were given 5 types
of treatment with concentrations of 5%, 10%, and 15%, positive control and negative control, with 25 samples. Using SPSS, the data were analysed using
the chi-square test. It was concluded that soursop fruit extract had an inhibitory effect on C.albicans clinical isolates from HPAR denture users, with the ave
rage inhibitory effect increasing with increasing concentration